![]() ![]() ![]() Check with your doctor first before taking any other medicines. John's wort, amphetamines, or some pain medicines (eg, tramadol, sumatriptan, zolmitriptan, or rizatriptan ). Duloxetine may cause serious conditions called serotonin syndrome or neuroleptic malignant syndrome (NMS)-like reactions if taken with certain medicines such as buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), lithium (Eskalith®, Lithobid®), tryptophan, St. Make sure your doctor knows about all the other medicines you are using. These could be symptoms of a serious liver problem. Let the doctor know if you or anyone in your family has bipolar disorder (manic-depressive) or has tried to commit suicide.Ĭheck with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. ![]() If you or your caregiver notice any of these unwanted effects, tell your doctor right away. Some people may have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. Ask your doctor if you are not sure if you take an MAOI, including linezolid (Zyvox®) or methylene blue injection.ĭuloxetine may cause some teenagers and young adults to be agitated, irritable, or display other abnormal behaviors. If you do, you may develop confusion, agitation, restlessness, stomach or intestinal symptoms, sudden high body temperature, extremely high blood pressure, or severe convulsions. Do not start taking an MAO inhibitor within 5 days of stopping duloxetine. It is important that your doctor check your progress at regular visits to allow for changes in your dose and to help prevent any unwanted effects.ĭo not take duloxetine with a monoamine oxidase (MAO) inhibitor (eg, isocarboxazid, phenelzine, selegiline, or tranylcypromine ) in the past 2 weeks. Children younger than 13 years of age-Use and dose must be determined by your doctor.However, the dose is usually not more than 60 mg per day. Your doctor may increase your dose as needed. Children 13 years of age and older-At first, 30 mg once a day.However, the dose is usually not more than 120 mg per day.įor treatment of diabetic peripheral neuropathy: Adults-40 milligrams (mg) per day (given as 20 mg two times per day) to 60 mg per day (given either once a day or as 30 mg two times per day).Children-Use and dose must be determined by your doctor.Some patients may start at 30 mg once a day for 1 week before increasing the dose to 60 mg once a day. Children younger than 7 years of age-Use and dose must be determined by your doctor.However, the dose is usually not more than 120 mg per day. Children 7 years of age and older-At first, 30 mg once a day for 2 weeks before increasing the dose to 60 mg once a day.Older adults-At first, 30 mg once a day for 2 weeks before increasing the dose to 60 mg once a day.Adults-At first, 60 milligrams (mg) once a day.Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.įor oral dosage form (delayed-release capsules): The amount of medicine that you take depends on the strength of the medicine. If your dose is different, do not change it unless your doctor tells you to do so. The following information includes only the average doses of this medicine. Follow your doctor's orders or the directions on the label. The dose of this medicine will be different for different patients. ![]()
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